EMBL Advanced Course on "Hybrid Structural Biology Approaches"
Hamburg, 11-16 June 2012, co-sponsored by P-CUBE
Organisers: Victor Lamzin, Rob Meijers, Carsten Sachse, Thomas Schneider, Dmitri Svergun, Matthias Wilmanns, Rosemary Wilson (all EMBL Hamburg, Germany)

From the 11th – 16th June 2012, EMBL Hamburg hosted the first EMBL Advanced Course on Hybrid Structural Biology Approaches. Sixteen students from across Europe attended the 6 day course which included lectures and practical sessions on Sample Preparation and Characterization, Small Angle X-ray Scattering, Macromolecular Crystallography and Electron Microscopy. The second half of the course included software demonstrations on how to evaluate and combine the data from the different techniques.
Highlights also included plenary talks by Jean van den Elsen from the University of Bath, UK on using a hybrid structural biology approach for a multienzyme complex assembly, and Savvas Savvides from the University of Gent in Belgium who spoke about the diversity of hematopoietic cytokine-receptor complexes revealed by hybrid methods in structural biology. The students also presented their own research in a number of lively sessions.
The feedback from the students was generally positive, and the overall feeling was that the course was a success. “The atmosphere of the course has been great and it has been good to hear how other groups use hybrid approaches to tackle their research projects. I now have a good overview of the techniques presented here and ideas on how to move forward with my own research” said one participant. “Hybrid approaches in structural biology are becoming more and more important.” said Matthias Wilmanns ,head of EMBL Hamburg and one of the course organizers, “Bringing together students and experts from different scientific backgrounds has led to a lively exchange of ideas and thoughts. We hope this is something that can be transferred to the entire structural biology community”.
The course was supported by the EU projects BioStruct-X, Instruct and PCUBE. For access to the course material please contact
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